PT-141, also known as bremelanotide, is a synthetic peptide that is used to treat female hypoactive sexual desire disorder (HSDD). HSDD is a condition characterized by a persistent lack of interest in sexual activity. It is a common condition that affects women of all ages.
PT-141 is a self-injectable medication that is typically injected subcutaneously (under the skin) in the abdomen or thigh. It is injected 45-60 minutes before sexual activity. The effects of PT-141 last for about 2-4 hours.
PT-141 works by stimulating the release of dopamine and nitric oxide in the brain. Dopamine is a neurotransmitter that plays a role in motivation, reward, and sexual pleasure. Nitric oxide is a vasodilator, meaning that it widens blood vessels. This can increase blood flow to the genitals, which can lead to improved sexual function.
PT-141 is generally well-tolerated, but it can cause some side effects, such as:
- Flushing
- Headache
- Dizziness
- Nausea
- Nasal congestion
- Back pain
- Injection site reactions
More serious side effects, such as hypotension (low blood pressure) and syncope (fainting), are rare.
PT-141 is not yet approved by the FDA for the treatment of any other condition, but it is being investigated for the treatment of erectile dysfunction (ED) in men, premature ejaculation (PE) in men, and sexual dysfunction associated with spinal cord injury (SCI).
Here are some additional things to know about PT-141:
- PT-141 is not a hormone replacement therapy (HRT).
- PT-141 is not addictive.
- PT-141 is not a birth control pill.
- PT-141 should not be used by women who are pregnant or breastfeeding.
- PT-141 should not be used by people with certain medical conditions, such as heart disease, kidney disease, or liver disease.
If you are considering using PT-141, be sure to talk to your doctor about the risks and benefits.
Here are some of the potential benefits of using PT-141:
- Increased sexual desire
- Increased sexual arousal
- Improved sexual function
- Increased sexual satisfaction
- Improved self-esteem
- Improved relationships
If you are experiencing HSDD, PT-141 may be a treatment option for you. Talk to your doctor to learn more about PT-141 and to see if it is right for you.
