Pentosan polysulfate sodium (PPS), also known as Elmiron, is a prescription medication used to treat bladder pain syndrome/interstitial cystitis (BPS/IC). BPS/IC is a chronic bladder condition that causes pain, pressure, and discomfort in the bladder and pelvic region. PPS is thought to work by coating and protecting the lining of the bladder, which can help to reduce inflammation and pain.
PPS is typically taken orally, once or three times a day. The dosage of PPS will vary depending on the individual patient’s needs. PPS is generally well-tolerated, but some side effects may include nausea, vomiting, diarrhea, headache, and dizziness.
PPS is the only FDA-approved medication for the treatment of BPS/IC. It is a safe and effective medication for most people with BPS/IC. However, some people may not respond to PPS or may experience side effects that make it not a good option for them.
Here are some of the benefits of PPS for BPS/IC:
- Reduces bladder pain and discomfort
- Improves bladder capacity
- Reduces the frequency of urination
- Improves quality of life
PPS is not a cure for BPS/IC, but it can help to manage the symptoms of the condition and improve the quality of life for people with BPS/IC.
If you are considering taking PPS, it is important to talk to your doctor first. Your doctor can help you to determine if PPS is right for you and can monitor you for any side effects.
Here are some of the risks and side effects of PPS:
- Nausea
- Vomiting
- Diarrhea
- Headache
- Dizziness
- Hair loss
- Pigmentary maculopathy (a rare eye condition that can lead to vision loss)
If you experience any side effects while taking PPS, be sure to talk to your doctor.
Other potential uses of PPS
In addition to its use for BPS/IC, PPS is also being investigated for potential use in the treatment of other conditions, including:
- Osteoarthritis
- Painful bowel syndrome
- Vulvodynia
- Interstitial cystitis in men
- Radiation cystitis
- Chemotherapy-induced cystitis
- Overactive bladder
- Recurrent urinary tract infections
Research on the use of PPS for these conditions is still ongoing, but the results so far have been promising.
PPS is a safe and effective medication for the treatment of BPS/IC. It is the only FDA-approved medication for this condition. PPS is also being investigated for potential use in the treatment of other conditions, such as osteoarthritis, painful bowel syndrome, vulvodynia, and interstitial cystitis in men.
If you are considering taking PPS, it is important to talk to your doctor first. Your doctor can help you to determine if PPS is right for you and can monitor you for any side effects.
