MK-677, also known as ibutamoren, is a growth hormone secretagogue (GHS) that mimics the effects of the natural hormone ghrelin. Ghrelin is a peptide hormone that is released by the stomach and stimulates the release of growth hormone from the pituitary gland.
MK-677 is a potent oral GHS that has been shown to increase growth hormone levels by up to 20-fold. It is also a long-acting GHS, with a half-life of 4-6 hours.
MK-677 is not yet approved by the FDA for any use in humans, but it is being investigated for a variety of potential therapeutic applications, including:
- Growth hormone deficiency: MK-677 is being investigated for the treatment of growth hormone deficiency in children and adults. Growth hormone deficiency can cause a variety of problems, including short stature, delayed puberty, and decreased bone density.
- Muscle wasting: MK-677 is being investigated for the treatment of muscle wasting conditions, such as cachexia and sarcopenia. Cachexia is a condition characterized by severe muscle wasting and loss of body fat. Sarcopenia is a condition characterized by the loss of muscle mass and strength that occurs with age.
- Osteoporosis: MK-677 is being investigated for the treatment of osteoporosis, a condition characterized by weak and brittle bones.
- Wound healing: MK-677 is being investigated for its ability to promote wound healing.
- Athletic performance: MK-677 is being investigated for its potential to improve athletic performance.
MK-677 is generally safe and well-tolerated. However, it can cause some side effects, such as:
- Increased appetite
- Weight gain
- Headache
- Nausea
- Vomiting
- Joint pain
- Muscle pain
- Insomnia
MK-677 can also interact with other medications. If you are taking any other medications, talk to your doctor before taking MK-677.
MK-677 is a potent oral GHS that is being investigated for a variety of potential therapeutic applications. It is generally safe and well-tolerated, but it can cause some side effects. If you are considering taking MK-677, talk to your doctor first.
Important note: MK-677 is a research chemical and is not approved for human use. It is important to be aware of the potential risks and side effects before taking MK-677.
