Ammonium tetrathiomolybdate (ATM) peptides are a class of synthetic peptides that contain ATM as a functional group. They are being investigated for the treatment of a variety of diseases, including:
- Wilson’s disease: ATM peptides are effective in the treatment of Wilson’s disease, a genetic disorder that causes copper to accumulate in the body. ATM peptides work by binding to copper and preventing it from being absorbed by the body. ATM peptides also help to remove copper from the body through the urine.
- Cancer: ATM peptides have been shown to have anti-cancer activity in preclinical studies. They work by killing cancer cells and by preventing tumor growth. ATM peptides are currently being investigated for the treatment of a variety of cancers in clinical trials.
- Alzheimer’s disease: ATM peptides have been shown to protect neurons from damage in preclinical studies of Alzheimer’s disease. Alzheimer’s disease is a neurodegenerative disorder that causes damage to neurons in the brain. ATM peptides are currently being investigated for the treatment of Alzheimer’s disease in clinical trials.
- Parkinson’s disease: ATM peptides have been shown to protect neurons from damage in preclinical studies of Parkinson’s disease. Parkinson’s disease is a neurodegenerative disorder that causes damage to neurons in the brain that produce dopamine. ATM peptides are currently being investigated for the treatment of Parkinson’s disease in clinical trials.
In addition to these diseases, ATM peptides are also being investigated for the treatment of a variety of other conditions, including:
- Infectious diseases: ATM peptides have been shown to have antimicrobial activity against a variety of bacteria, viruses, and fungi. ATM peptides are currently being investigated for the treatment of a variety of infectious diseases, including pneumonia, meningitis, and sepsis.
- Inflammatory diseases: ATM peptides have been shown to reduce inflammation in preclinical studies. ATM peptides are currently being investigated for the treatment of a variety of inflammatory diseases, including inflammatory bowel disease, rheumatoid arthritis, and multiple sclerosis.
- Neurological disorders: In addition to Alzheimer’s disease and Parkinson’s disease, ATM peptides are also being investigated for the treatment of a variety of other neurological disorders, including stroke, spinal cord injury, and amyotrophic lateral sclerosis (ALS).
ATM peptides are a promising class of therapeutic agents with a wide range of potential applications. More research is needed to confirm the safety and efficacy of ATM peptides for the treatment of all of these diseases and conditions, but they have the potential to revolutionize the treatment of a variety of diseases.
How ATM peptides work
ATM peptides work in a variety of ways to produce their therapeutic effects. One common mechanism of action is their ability to bind to copper. Copper is a toxic metal, and its accumulation in the body can lead to damage to the liver, brain, and other organs. ATM peptides bind to copper and prevent it from being absorbed by the body. ATM peptides also help to remove copper from the body through the urine.
Another common mechanism of action of ATM peptides is their ability to kill cancer cells. ATM peptides work by disrupting the cell membranes of cancer cells. This disruption causes the cancer cells to leak and die.
ATM peptides can also protect neurons from damage. ATM peptides do this by reducing inflammation and by preventing the production of toxic molecules.
ATM peptides in clinical trials
ATM peptides are currently being investigated in clinical trials for the treatment of a variety of diseases. Some of the most promising clinical trials include:
- Wilson’s disease: ATM peptides have been shown to be safe and effective in clinical trials for the treatment of Wilson’s disease. ATM peptides are now the standard of care for the treatment of Wilson’s disease.
- Cancer: ATM peptides are currently being investigated in clinical trials for the treatment of a variety of cancers, including pancreatic cancer, lung cancer, and breast cancer. The results of these trials are promising, but more research is needed to confirm the safety and efficacy of ATM peptides for the treatment of cancer.
- Alzheimer’s disease: ATM peptides are currently being investigated in clinical trials for the treatment of Alzheimer’s disease. The results of these trials are promising, but more research is needed to confirm the safety and efficacy of ATM peptides for the treatment of Alzheimer’s disease.
