Dihexa (developmental code name PNB-0408) is a small oligopeptide drug derived from angiotensin IV. It is currently being investigated for the treatment of Alzheimer’s disease and other neurological disorders.
Dihexa is thought to work by potentiating the activity of hepatocyte growth factor (HGF) at its receptor, c-Met. HGF is a potent neurotrophic factor that plays an important role in the development and maintenance of the nervous system. It also has neuroprotective and regenerative effects.
In animal studies, Dihexa has been shown to be safe and well-tolerated. However, some people may experience side effects such as:
- Nausea
- Vomiting
- Diarrhea
- Headache
- Jitters
- Irritability
In some cases, Dihexa may also cause withdrawal symptoms if it is stopped suddenly. These symptoms can include irritability and anxiety.
It is important to note that Dihexa is still in the early stages of clinical development, and more research is needed to fully understand its safety and side effects profile.
Risk factors for side effects
Certain people may be at increased risk of experiencing side effects from Dihexa. These people include:
- People with underlying medical conditions, such as liver disease, kidney disease, or heart disease
- People who are taking other medications
- Pregnant or breastfeeding women
How to minimize the risk of side effects
There are a few things that people can do to minimize the risk of experiencing side effects from Dihexa:
- Start with a low dose and increase the dose gradually
- Take Dihexa with food to reduce the risk of stomach upset
- Avoid taking Dihexa with other medications that may interact with it
- Talk to your doctor about any concerns you have about side effects
Dihexa is a promising new drug for the treatment of Alzheimer’s disease and other neurological disorders. However, it is important to be aware of the potential side effects of Dihexa before taking it. If you are considering taking Dihexa, talk to your doctor about the risks and benefits.
