Ammonium tetrathiomolybdate (ATM) peptides are a class of synthetic peptides that contain ATM as a functional group. ATM is a chemical compound that is known to bind to copper and to have anti-inflammatory and antioxidant properties.
ATM peptides are being investigated for a wide range of potential applications, including:
- Wilson’s disease: ATM peptides are effective in the treatment of Wilson’s disease, a genetic disorder that causes copper to accumulate in the body.
- Cancer: ATM peptides have been shown to have anti-cancer activity in preclinical studies.
- Alzheimer’s disease: ATM peptides have been shown to protect neurons from damage in preclinical studies of Alzheimer’s disease.
- Parkinson’s disease: ATM peptides have been shown to protect neurons from damage in preclinical studies of Parkinson’s disease.
- Infectious diseases: ATM peptides have been shown to have antimicrobial activity against a variety of bacteria, viruses, and fungi.
- Inflammatory diseases: ATM peptides have been shown to reduce inflammation in preclinical studies.
- Neurological disorders: In addition to Alzheimer’s disease and Parkinson’s disease, ATM peptides are also being investigated for the treatment of a variety of other neurological disorders, including stroke, spinal cord injury, and amyotrophic lateral sclerosis (ALS).
ATM peptides are generally safe and well-tolerated, but some people may experience side effects. The most common side effects of ATM peptides are:
- Gastrointestinal upset: ATM peptides can cause gastrointestinal upset, such as nausea, vomiting, and diarrhea.
- Hypotension: ATM peptides can cause hypotension, or low blood pressure.
- Allergic reactions: ATM peptides can cause allergic reactions in some people. Symptoms of an allergic reaction can include hives, swelling, difficulty breathing, and anaphylaxis.
Other possible side effects of ATM peptides include:
- Skin irritation: ATM peptides can irritate the skin, especially when applied topically.
- Headache: ATM peptides can cause headaches.
- Fatigue: ATM peptides can cause fatigue.
- Dizziness: ATM peptides can cause dizziness.
- Hair loss: ATM peptides can cause hair loss.
It is important to note that the side effects of ATM peptides may vary depending on the specific peptide and its intended use. For example, an ATM peptide that is being developed for the treatment of Wilson’s disease may have different side effects than an ATM peptide that is being developed for the treatment of cancer.
If you are considering taking ATM peptides, it is important to talk to your doctor about the potential risks and benefits. Your doctor can help you determine if ATM peptides are right for you and can monitor you for any side effects.
How to reduce the risk of side effects
There are a few things you can do to reduce the risk of side effects from ATM peptides:
- Take the lowest effective dose. ATM peptides are effective at a wide range of doses. Taking the lowest effective dose can help to reduce the risk of side effects.
- Take ATM peptides with food. Taking ATM peptides with food can help to reduce gastrointestinal upset.
- Drink plenty of fluids. Drinking plenty of fluids can help to prevent dehydration, which can be a side effect of ATM peptides.
- Avoid alcohol and tobacco. Alcohol and tobacco can increase the risk of side effects from ATM peptides.
If you experience any side effects from ATM peptides, be sure to talk to your doctor. Your doctor may be able to reduce your dose or switch you to a different type of ATM peptide.
