Tesofensine peptide is a synthetic compound with the chemical formula C17H22N2O. It is a white solid with a melting point of 187-190 °C. Tesofensine peptide is a derivative of piperidine, a six-membered ring structure with a nitrogen atom at one corner. The piperidine ring is substituted with a number of functional groups, including a methyl group, a phenyl group, and a morpholino group.
Here is a diagram of the chemical structure of tesofensine peptide:
Tesofensine peptide is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). This means that it works by blocking the reuptake of serotonin, norepinephrine, and dopamine in the brain. Reuptake is the process by which these neurotransmitters are removed from the synapse (the space between two nerve cells) after they have been released. By blocking reuptake, tesofensine peptide increases the levels of these neurotransmitters in the brain.
Serotonin, norepinephrine, and dopamine are all involved in the regulation of appetite, mood, and energy expenditure. Increasing the levels of these neurotransmitters in the brain can lead to a number of effects, including:
- Reduced appetite
- Increased feelings of fullness
- Increased energy expenditure
- Improved mood
These effects can all contribute to weight loss.
Tesofensine peptide is currently in Phase III clinical trials for the treatment of obesity. The results of these trials are expected to be released in 2023. If tesofensine peptide is approved by the FDA, it would be the first new drug for the treatment of obesity to be approved in over a decade.
It is important to note that tesofensine peptide is not currently approved for any use, and more research is needed to confirm its safety and efficacy. If you are considering taking tesofensine peptide, it is important to talk to your doctor about the risks and benefits.
