MK-677, also known as ibutamoren, is a growth hormone secretagogue (GHS) that mimics the effects of the natural hormone ghrelin. Ghrelin is a peptide hormone that is released by the stomach and stimulates the release of growth hormone from the pituitary gland.
MK-677 is a non-peptide GHS, meaning that it is not made up of amino acids. Instead, it is a small molecule that is able to bind to ghrelin receptors and activate them.
The chemical structure of MK-677 is as follows:
2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4′-piperidine]-1′-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide
MK-677 is a white, crystalline powder that is soluble in water. It has a molecular weight of 528.67 grams per mole.
How MK-677 works
MK-677 works by binding to ghrelin receptors in the brain. This leads to increased production and release of growth hormone from the pituitary gland.
Growth hormone is a powerful hormone that plays a role in many bodily functions, including:
- Muscle growth and repair
- Bone growth and development
- Metabolism
- Fat burning
- Immune function
Potential uses of MK-677
MK-677 is not yet approved by the FDA for any use in humans, but it is being investigated for a variety of potential therapeutic applications, including:
- Growth hormone deficiency
- Muscle wasting
- Osteoporosis
- Wound healing
- Athletic performance
MK-677 is also popular among bodybuilders and other athletes for its ability to increase muscle mass and strength.
Side effects of MK-677
MK-677 is generally safe and well-tolerated. However, it can cause some side effects, such as:
- Increased appetite
- Weight gain
- Headache
- Nausea
- Vomiting
- Joint pain
- Muscle pain
- Insomnia
MK-677 can also interact with other medications. If you are taking any other medications, talk to your doctor before taking MK-677.
MK-677 is a potent oral GHS that has the potential to be a valuable therapeutic agent for a variety of conditions. However, it is important to remember that MK-677 is not yet approved for human use and more research is needed to confirm its safety and efficacy.
If you are considering taking MK-677, talk to your doctor first. They can help you to determine if MK-677 is right for you and can monitor you for any side effects.