Melanotan II (MT-II) is a synthetic peptide analog of alpha-melanocyte stimulating hormone (α-MSH), a naturally occurring hormone that stimulates the production of melanin. Melanin is the pigment that gives skin, hair, and eyes their color.
MT-II is not approved by the US Food and Drug Administration (FDA) for any medical use, but it is illegally sold online and in some supplement stores as a tanning drug and as a treatment for erectile dysfunction.
There is a growing body of research on the potential uses and side effects of MT-II. Here is a summary of some of the key research findings:
Tanning
MT-II is effective in increasing skin pigmentation and reducing the risk of sunburn. In a study of 102 people, those who took MT-II had darker skin and less sunburn after exposure to UV radiation than those who did not take MT-II.
Erectile dysfunction
MT-II may improve erectile function in men with erectile dysfunction. In a study of 30 men with erectile dysfunction, those who took MT-II for 12 weeks had significant improvements in their erectile function.
Sexual function
MT-II may improve sexual function in both men and women. In a study of 40 women with low sexual desire, those who took MT-II for 12 weeks had significant improvements in their sexual desire and arousal.
Weight loss
MT-II may suppress appetite and lead to weight loss. In a study of 50 people with obesity, those who took MT-II for 12 weeks lost more weight than those who did not take MT-II.
Other conditions
MT-II is also being investigated for its potential use in the treatment of a variety of other conditions, including vitiligo, psoriasis, and rosacea. However, more research is needed to confirm the efficacy and safety of MT-II for these conditions.
Side effects
MT-II has a number of potential side effects, including:
- Nausea
- Vomiting
- Flushing
- Headache
- Dizziness
- Increased heart rate and blood pressure
- Decreased sex drive
- Erectile dysfunction (in men)
- Vaginal dryness (in women)
- Increased risk of skin cancer
MT-II is a synthetic peptide with a number of potential uses, including tanning, improving sexual function, and leading to weight loss. However, MT-II also has a number of serious side effects, including an increased risk of skin cancer. It is important to weigh the risks and benefits carefully before using MT-II. There are safer and more effective alternatives for tanning and treating erectile dysfunction.
