Nicotinamide adenine dinucleotide (NAD+) is a coenzyme that plays a vital role in many cellular processes, including energy metabolism, DNA repair, and cell signaling. NAD+ levels decline with age, which is thought to contribute to a variety of age-related diseases and conditions.
NAD+ peptide supplements are a way to boost NAD+ levels in the body. NAD+ peptide supplements are generally safe, and they have been shown to have a number of potential benefits, including improved cognitive function, reduced risk of age-related diseases, increased lifespan, improved energy levels and endurance, reduced inflammation, improved muscle function, and improved skin health.
NAD+ peptide supplements work by increasing the production of NAD+ in the body. NAD+ can be produced through a number of different pathways, but the most important pathway is the salvage pathway. The salvage pathway uses nicotinamide (NAM) and nicotinamide riboside (NR) to produce NAD+.
NAD+ peptide supplements typically contain NR, which is a more efficient precursor to NAD+ than NAM. NR is converted to NAD+ in the body in two steps. The first step is catalyzed by the enzyme nicotinamide riboside kinase (NRK), and the second step is catalyzed by the enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT).
Once NAD+ levels are increased in the body, NAD+ can bind to and activate a variety of different enzymes. These enzymes are involved in a wide range of cellular processes, including energy metabolism, DNA repair, and cell signaling.
Here is a more detailed look at how NAD+ peptide supplements work to improve specific health conditions:
- Improved cognitive function: NAD+ is involved in a number of cellular processes that are important for brain health, such as energy metabolism, DNA repair, and cell signaling. Boosting NAD+ levels has been shown to improve cognitive function in animal models of Alzheimer’s disease and Parkinson’s disease.
- Reduced risk of age-related diseases: NAD+ levels decline with age, and this decline is thought to contribute to a variety of age-related diseases, such as Alzheimer’s disease, Parkinson’s disease, cardiovascular disease, and cancer. Boosting NAD+ levels may help to reduce the risk of these diseases by improving cellular function and protecting cells from damage.
- Increased lifespan: NAD+ levels have been shown to decline with age, and this decline is thought to play a role in the aging process. Boosting NAD+ levels has been shown to increase lifespan in animal models.
- Improved energy levels and endurance: NAD+ is essential for the production of ATP, the body’s main energy currency. Boosting NAD+ levels can lead to increased energy levels and endurance.
- Reduced inflammation: NAD+ has anti-inflammatory properties. Boosting NAD+ levels may help to reduce inflammation throughout the body.
- Improved muscle function: NAD+ is involved in muscle metabolism and repair. Boosting NAD+ levels may help to improve muscle function and reduce muscle loss.
- Improved skin health: NAD+ is involved in the production of collagen and elastin, which are two proteins that are essential for healthy skin. Boosting NAD+ levels may help to improve skin health and reduce the appearance of wrinkles and age spots.
If you are considering taking NAD+ peptide supplements, it is important to talk to your doctor first, especially if you have any underlying health conditions.