Ammonium tetrathiomolybdate (ATM) peptides are a class of synthetic peptides that contain ATM as a functional group. ATM is a chemical compound that is known to bind to copper and to have anti-inflammatory and antioxidant properties.
ATM peptides work in a variety of ways to produce their therapeutic effects, but one of the most important mechanisms of action is their ability to bind to copper. Copper is a metal that is essential for many biological processes, but it can also be toxic when it accumulates in the body. ATM peptides can bind to copper and prevent it from being absorbed by the body or from accumulating in tissues. This can be beneficial in a variety of diseases, including Wilson’s disease, cancer, and Alzheimer’s disease.
Wilson’s disease
Wilson’s disease is a genetic disorder that causes copper to accumulate in the body. Copper accumulation can lead to damage to the liver, brain, and other organs. ATM peptides are effective in the treatment of Wilson’s disease because they bind to copper and prevent it from accumulating in the body.
Cancer
ATM peptides have been shown to have anti-cancer activity in preclinical studies. ATM peptides can kill cancer cells by disrupting their cell membranes. ATM peptides can also prevent tumor growth by inhibiting the growth of new blood vessels that tumors need to grow.
Alzheimer’s disease
Alzheimer’s disease is a neurodegenerative disorder that causes damage to neurons in the brain. ATM peptides have been shown to protect neurons from damage in preclinical studies of Alzheimer’s disease. ATM peptides do this by reducing inflammation and by preventing the production of toxic molecules.
In addition to these mechanisms of action, ATM peptides are also being investigated for their potential to treat other diseases, such as infectious diseases, inflammatory diseases, and other neurological disorders.
How ATM peptides are delivered to the body
ATM peptides can be delivered to the body in a variety of ways, including:
- Oral: ATM peptides can be taken orally in the form of capsules or tablets.
- Intravenous: ATM peptides can be administered intravenously (into a vein).
- Topical: ATM peptides can be applied to the skin in the form of a cream or lotion.
The best route of administration for ATM peptides depends on the specific disease or condition being treated.
Safety and side effects of ATM peptides
ATM peptides are generally safe and well-tolerated. However, some people may experience side effects, such as:
- Skin irritation: ATM peptides can irritate the skin, especially when applied topically.
- Gastrointestinal upset: ATM peptides can cause gastrointestinal upset, such as nausea, vomiting, and diarrhea.
- Hypotension: ATM peptides can cause hypotension, or low blood pressure.
- Allergic reactions: ATM peptides can cause allergic reactions in some people. Symptoms of an allergic reaction can include hives, swelling, difficulty breathing, and anaphylaxis.
ATM peptides are a promising class of therapeutic agents with a wide range of potential applications. They are currently being investigated in clinical trials for the treatment of a variety of diseases, including Wilson’s disease, cancer, and Alzheimer’s disease. ATM peptides are generally safe and well-tolerated, but some people may experience side effects.
