5-amino-1MQ peptide, also known as 5-amino-1-methylquinoline, is a small molecule drug that works by inhibiting an enzyme called nicotinamide N-methyltransferase (NNMT). NNMT is an enzyme that plays a role in regulating metabolism and energy production. It is most active in fat tissue, where it converts nicotinamide (NAM) to 1-methylnicotinamide (1-MNA). 1-MNA is a byproduct of metabolism that can accumulate in fat cells and lead to insulin resistance and other metabolic problems.
By blocking NNMT, 5-amino-1MQ increases levels of NAM in the body. NAM is a precursor to nicotinamide adenine dinucleotide (NAD+), a cofactor that is essential for many cellular processes, including metabolism, energy production, and DNA repair. NAD+ levels decline with age, which is thought to contribute to the development of age-related diseases such as obesity, diabetes, and heart disease. 5-amino-1MQ may help to protect against these diseases by increasing NAD+ levels in the body.
Here is a more detailed explanation of how 5-amino-1MQ peptide works:
- Inhibition of NNMT: NNMT is an enzyme that transfers a methyl group from S-adenosyl methionine (SAM) to NAM. This process produces 1-MNA and S-adenosyl homocysteine (SAH). 1-MNA is a byproduct of metabolism that can accumulate in fat cells and lead to insulin resistance and other metabolic problems. SAH is an inhibitor of NAD+ synthesis.
5-amino-1MQ peptide works by inhibiting NNMT. This prevents the conversion of NAM to 1-MNA and SAH. It also allows for more NAM to be available for NAD+ synthesis.
- Increased NAD+ levels: NAD+ is a cofactor that is essential for many cellular processes, including metabolism, energy production, and DNA repair. NAD+ levels decline with age, which is thought to contribute to the development of age-related diseases such as obesity, diabetes, and heart disease.
5-amino-1MQ peptide increases NAD+ levels in the body by inhibiting NNMT. This allows for more NAM to be available for NAD+ synthesis.
- Improved metabolism: NAD+ plays a role in regulating metabolism. It is essential for the proper function of mitochondria, which are the organelles responsible for energy production.
By increasing NAD+ levels, 5-amino-1MQ peptide can improve metabolism. This can lead to weight loss and improved metabolic health.
- Reduced inflammation: Inflammation is a normal immune response that helps to protect the body from infection and injury. However, chronic inflammation can contribute to the development of many diseases, including obesity, diabetes, and heart disease.
NAD+ has anti-inflammatory properties. By increasing NAD+ levels, 5-amino-1MQ peptide can help to reduce inflammation.
- Improved cognitive function: NAD+ also plays a role in cognitive function. It is essential for the proper function of neurons, which are the cells that make up the nervous system.
By increasing NAD+ levels, 5-amino-1MQ peptide may help to improve cognitive function.
Overall, 5-amino-1MQ peptide works by inhibiting NNMT and increasing NAD+ levels in the body. This can lead to a number of health benefits, including weight loss, improved metabolic health, reduced inflammation, and improved cognitive function.
More research is needed
5-amino-1MQ peptide is a promising new drug with the potential to promote weight loss, improve metabolic health, extend lifespan, and improve cognitive function. However, more research is needed to confirm these benefits and to determine the long-term safety of 5-amino-1MQ peptide.
If you are considering taking 5-amino-1MQ peptide, it is important to talk to your doctor to see if it is right for you.
