Glycyrrhetinic acid (GA) is also known as:
- Enxolone
- Glycyrrhizic acid aglycone
- 30-Nor-18β-olean-12-en-3α-ol-28-oic acid
- Glycyrrhizin sapogenin
- Glycyrrhetinic acid monoglucuronide
- Glycyrrhetinic acid monoglucuronide sodium
These are all different names for the same compound, which is a triterpenoid compound found in the root of the licorice plant (Glycyrrhiza glabra). GA is the main active ingredient in licorice root extract and is responsible for its sweet taste and many medicinal properties.
GA has a wide range of biological activities, including:
- Anti-inflammatory
- Antiviral
- Antimicrobial
- Antioxidant
- Anticancer
- Hepatoprotective
- Wound healing
- Immunomodulatory
GA is being investigated for its potential to treat a wide range of diseases and conditions, including:
- Inflammatory bowel disease
- Hepatitis C virus infection
- Colorectal cancer
- Alzheimer’s disease
- Parkinson’s disease
- Multiple sclerosis
- Cardiovascular disease
GA is generally safe for most people when consumed in moderation. However, high doses of GA can cause side effects such as high blood pressure, muscle weakness, and potassium loss. GA should be avoided by people with kidney disease, high blood pressure, or heart disease.
GA is available in a variety of forms, including capsules, tablets, powder, and liquid extract. It is also found in many herbal supplements and topical products.
If you are considering using GA, please talk to your doctor to determine if it is right for you.
