Ammonium tetrathiomolybdate (ATM) peptides are a class of synthetic peptides that contain ATM as a functional group. ATM is a chemical compound that is known to bind to copper and to have anti-inflammatory and antioxidant properties.
ATM peptides are being investigated for a wide range of potential applications, including:
- Wilson’s disease: ATM peptides are effective in the treatment of Wilson’s disease, a genetic disorder that causes copper to accumulate in the body.
- Cancer: ATM peptides have been shown to have anti-cancer activity in preclinical studies.
- Alzheimer’s disease: ATM peptides have been shown to protect neurons from damage in preclinical studies of Alzheimer’s disease.
- Parkinson’s disease: ATM peptides have been shown to protect neurons from damage in preclinical studies of Parkinson’s disease.
- Infectious diseases: ATM peptides have been shown to have antimicrobial activity against a variety of bacteria, viruses, and fungi.
- Inflammatory diseases: ATM peptides have been shown to reduce inflammation in preclinical studies.
- Neurological disorders: In addition to Alzheimer’s disease and Parkinson’s disease, ATM peptides are also being investigated for the treatment of a variety of other neurological disorders, including stroke, spinal cord injury, and amyotrophic lateral sclerosis (ALS).
Here are some specific examples of the potential uses of ATM peptides:
Wilson’s disease
Wilson’s disease is a genetic disorder that causes copper to accumulate in the liver, brain, and other organs. This can lead to serious health problems, such as liver failure, neurological problems, and psychiatric symptoms.
ATM peptides can be used to treat Wilson’s disease by binding to copper and preventing it from accumulating in the body. This can help to improve symptoms and prevent further damage to organs.
Cancer
ATM peptides have been shown to have anti-cancer activity in preclinical studies. They work by disrupting the cell membranes of cancer cells, causing them to leak and die. ATM peptides can also prevent tumor growth by inhibiting the growth of new blood vessels that tumors need to grow.
ATM peptides are currently being investigated in clinical trials for the treatment of a variety of cancers, including pancreatic cancer, lung cancer, and breast cancer. The results of these trials are promising, but more research is needed to confirm the safety and efficacy of ATM peptides for the treatment of cancer.
Alzheimer’s disease
Alzheimer’s disease is a neurodegenerative disorder that causes damage to neurons in the brain. This damage leads to memory loss, cognitive decline, and other symptoms.
ATM peptides have been shown to protect neurons from damage in preclinical studies of Alzheimer’s disease. They do this by reducing inflammation and by preventing the production of toxic molecules.
ATM peptides are currently being investigated in clinical trials for the treatment of Alzheimer’s disease. The results of these trials are promising, but more research is needed to confirm the safety and efficacy of ATM peptides for the treatment of Alzheimer’s disease.
Other potential uses
ATM peptides are also being investigated for the treatment of a variety of other diseases and conditions, including:
- Parkinson’s disease
- Infectious diseases
- Inflammatory diseases
- Neurological disorders
- Wound healing
- Pain
ATM peptides are a promising class of therapeutic agents with a wide range of potential applications. More research is needed to confirm the safety and efficacy of ATM peptides for the treatment of all of these diseases and conditions, but they have the potential to revolutionize the treatment of a variety of diseases.
It is important to note that ATM peptides are still under development. Most of the research on ATM peptides has been conducted in preclinical studies, and more clinical trials are needed to confirm their safety and efficacy in humans.
