Structure of ammonium tetrathiomolybdate (ATM) peptides
Ammonium tetrathiomolybdate (ATM) peptides are a class of synthetic peptides that contain ATM as a functional group. ATM is a chemical compound that is known to bind to copper and to have anti-inflammatory and antioxidant properties.
ATM peptides typically have a simple structure, consisting of a short chain of amino acids with an ATM molecule attached to the N-terminus (the beginning of the peptide chain). The ATM molecule is typically attached to the peptide chain through a cysteine residue, which is an amino acid that contains a sulfur atom.
The structure of the ATM molecule itself is tetrahedral, with the molybdenum atom at the center and the four sulfur atoms at the corners. The ammonium ions are located outside of the tetrahedral structure.
The structure of the ATM peptide will vary depending on the specific amino acid sequence of the peptide. However, all ATM peptides will have the same basic structure, with an ATM molecule attached to the N-terminus of the peptide chain.
Properties of ATM peptides
ATM peptides are generally water-soluble and have a low molecular weight. This makes them easy to deliver to the body and to target specific tissues.
ATM peptides are also relatively stable, meaning that they can withstand degradation in the body. This is important because it allows ATM peptides to have a long-lasting effect.
Potential applications of ATM peptides
ATM peptides are being investigated for a wide range of potential applications, including:
- Wilson’s disease: ATM peptides are effective in the treatment of Wilson’s disease, a genetic disorder that causes copper to accumulate in the body.
- Cancer: ATM peptides have been shown to have anti-cancer activity in preclinical studies.
- Alzheimer’s disease: ATM peptides have been shown to protect neurons from damage in preclinical studies of Alzheimer’s disease.
- Parkinson’s disease: ATM peptides have been shown to protect neurons from damage in preclinical studies of Parkinson’s disease.
- Infectious diseases: ATM peptides have been shown to have antimicrobial activity against a variety of bacteria, viruses, and fungi.
- Inflammatory diseases: ATM peptides have been shown to reduce inflammation in preclinical studies.
- Neurological disorders: In addition to Alzheimer’s disease and Parkinson’s disease, ATM peptides are also being investigated for the treatment of a variety of other neurological disorders, including stroke, spinal cord injury, and amyotrophic lateral sclerosis (ALS).
ATM peptides are a promising class of therapeutic agents with a wide range of potential applications. They are currently being investigated in clinical trials for the treatment of a variety of diseases, including Wilson’s disease, cancer, and Alzheimer’s disease. ATM peptides are generally safe and well-tolerated, but some people may experience side effects.
More research is needed to confirm the safety and efficacy of ATM peptides for the treatment of all of these diseases and conditions, but they have the potential to revolutionize the treatment of a variety of diseases.
