The structure of 5-amino-1MQ peptide is as follows:
[5-amino-1-methylquinoline]
N
/ \
/ \
/ \
H N
/ \
/ \
H C
/ \
H H
C H
/ \
H H
H H
N H
5-amino-1MQ peptide is a heterocyclic compound, meaning that it contains a ring of atoms that includes at least one element other than carbon. In the case of 5-amino-1MQ peptide, the ring is a six-membered quinoline ring.
The quinoline ring is substituted with two groups: an amino group at position 5 and a methyl group at position 1. The amino group is what gives 5-amino-1MQ peptide its name. The methyl group is what makes 5-amino-1MQ peptide a methylquinoline compound.
The structure of 5-amino-1MQ peptide is similar to the structure of nicotinamide (NAM), which is a precursor to nicotinamide adenine dinucleotide (NAD+), a cofactor that is essential for many cellular processes. This similarity in structure allows 5-amino-1MQ peptide to bind to NNMT and inhibit its activity.
More about NNMT
NNMT is an enzyme that transfers a methyl group from S-adenosyl methionine (SAM) to NAM. This process produces 1-methylnicotinamide (1-MNA) and S-adenosyl homocysteine (SAH). 1-MNA is a byproduct of metabolism that can accumulate in fat cells and lead to insulin resistance and other metabolic problems. SAH is an inhibitor of NAD+ synthesis.
By inhibiting NNMT, 5-amino-1MQ peptide prevents the conversion of NAM to 1-MNA and SAH. It also allows for more NAM to be available for NAD+ synthesis.
More about NAD+
NAD+ is a cofactor that is essential for many cellular processes, including metabolism, energy production, and DNA repair. NAD+ levels decline with age, which is thought to contribute to the development of age-related diseases such as obesity, diabetes, and heart disease. 5-amino-1MQ peptide may help to protect against these diseases by increasing NAD+ levels in the body.
5-amino-1MQ peptide is a promising new drug with the potential to promote weight loss, improve metabolic health, extend lifespan, and improve cognitive function. It works by inhibiting an enzyme called NNMT, which plays a role in regulating metabolism and energy production.
More research is needed to confirm the potential benefits of 5-amino-1MQ peptide and to determine its long-term safety. However, the results of preclinical and clinical studies to date suggest that 5-amino-1MQ peptide has the potential to be a valuable new therapeutic agent.
If you are considering taking 5-amino-1MQ peptide, it is important to talk to your doctor to see if it is right for you.
